Many people show symptoms of "space sickness," such as headaches, nausea, and vomiting.
In the low gravity of space, the information received from the vestibular organs changes.
This is thought to confuse the brain, leading to space sickness.
But this condition does not continue for very long.
If you stay for a few days in space, your brain adjusts its interpretation of the vestibular information, so the space sickness goes away.
When you return to earth, you experience the effects of earth's gravity again, and thus "gravity sickness" sometimes occurs, with similar symptoms as space sickness.
If you stay for a while in space, the fluids in your body balance out, and facial swelling typically begins to disappear after a few weeks.
Conversely, astronauts returning to earth often experience dizziness when standing up, known as orthostatic hypotension.
This occurs because gravity on the earth is stronger than in space, and it is more difficult to deliver blood from the heart to the head.
In space, blood can be delivered with less force, so weakening of the heart muscles may also be a cause of dizziness when standing.
If you stay for a long time in space, your muscles and bones will weaken, primarily in the legs and lower back.
Muscles weaken and bone mass decreases if you stay for a long time in space.
In outer space, with no atmosphere, radiation is more intense and has major impacts on the human body.
If a person is exposed to a lot of higher energy radiation, the risk increases that they will develop diseases such as cancer.
Astronauts develop stress before even realizing it when living and working together in a cramped space with other astronauts for a few months.
The astronauts on the ISS come from different places, including Russia, America, Canada, Europe, and Japan, so factors such as language barriers and cultural differences may also lead to stress.